Sorry I don't have an account, but I love the Big Bang. So here's a plot bunny: I'd love to see some backstory about House (and Wilson) dealing with treating Esther. She's the patient who died many years ago and House had been beating himself up ever since, wondering what he missed. I get the feeling he cared too much about her, and maybe she's part of the reason he hates dealing with patients now so he won't start to care about them.
House and Esther
Philtrum